Top Five Most Valuable Mewtwo Pokemon Cards

Mewtwo cards like the Mewtwo V can be a valuable asset for those who understand their market value, especially the rare versions from the Base Set or Gold Star. The value of Mewtwo cards varies, with the most valuable cards being those with printing errors or from earlier collections—able to fetch thousands of dollars.

Mewtwo is one of the franchise's most popular and recognizable Pokemon characters and is also one of the rarest cards to find—which adds to its value.

Additionally, some Mewtwo cards are considered "first edition," which refers to the initial print run of a particular set of cards. First-edition cards are generally considered to be more valuable than their later printings.

Finally, the card's condition also plays a role in determining its value, with high-grade or "gem mint" condition cards commanding a higher price. Mewtwo's popularity, rarity, and condition contribute to its value and make cards highly coveted among collectors.

Whether you're an avid collector or just starting out, here’s a list of the most valuable Mewtwo Pokemon cards and the prices you’re likely to find them at. So keep reading and, hopefully, you'll find one worth your attention.

1. 1999 Pokemon Game Mewtwo-Holo #10

• Price Range: $6 to $850
• Highest Sale Price: $3,300
• PSA 10 Supply: 527

The Mewtwo card with the holofoil is a popular collectible with a market value ranging from $11 to $850. It’s categorized as a base set holo and is part of the unlimited set released in 1999.

While some collectors do not consider it as rare and valuable as the 1st edition Mewtwo, it still holds a high rank among collectors. Due to its status as part of the first set, many collectors are willing to pay a good price for the card, with records showing that a PSA 10 sold for $3,300 in October 2020.

2. 1999 Pokemon Game Mewtwo-Holo Shadowless #10

• Price Range: $22 to $5,500
• Highest Sale Price: $8,300
• PSA 10 Supply: 69

The shadowless variant of the first edition Mewtwo-Holo #10 card is super scarce and sought-after by hardcore Pokemon card collectors. The card’s price range falls between $22 to $5,500 depending on its condition—its highest recorded sale fetched $8,299 in a February 2021 eBay auction.

In March 2023, eBay's probstein123 auctioned a PSA 10 card for $3,383, while seller ghoultech auctioned a gem mint for a slightly lower price of $2,100.

3. 2002 Pokemon Neo Destiny Shining Mewtwo 1st Edition #109

• Price Range: $240 to $4,000
• Highest Sale Price: $6,750
• PSA 10 Supply: 207

The 2002 Pokemon Neo Destiny Shining Mewtwo 1st Edition card ranges in price from several hundred dollars to a couple of thousand.

Its highest sale value of $6,750 remains significant—but you can try bargaining between $200 and $4,000 at the current market valuation.

4. 2005 Pokemon Japanese Gift Box Mew Mewtwo-Holo Gold Star #002

• Price Range: $40 to $1,000
• Highest Sale Price: $2,000
• PSA 10 Supply: 232

This Gold Star card holds a special place in the hearts of collectors because of its intricate Mewtwo illustration by Masakazu Fukuda.

While cards in poorer condition may come cheaper, the 2005 Pokemon Japanese Gift Box Mew Mewtwo-Holo Gold Star #002 has shown incremental value when graded near-mint or mint, with prices exceeding $1,000 for gem mint-graded cards.

5. 2001 Pokemon Japanese Neo 4 Shining Mewtwo #150

• Price Range: $51 to $4,500
• Highest Sale Price: $9,100
• PSA 10 Supply: 58

The 2001 Pokemon Japanese Neo 4 Shining Mewtwo card ranges from $51 to $4,500. We saw it sell for $8,500 In February 2023 but then drop back to $5,550 around the same time.

But the highest sale price ever recorded was $9,100 in April 2023, which shows a glimpse of its future potential. With 58 cards graded PSA 10 on record, this Mewtwo is certainly a rare and valuable collectible.

The worth of Mewtwo Pokemon cards like Mewtwo V depends on various aspects such as age, rarity, artwork, utility, and popularity. Over time, prices of certain cards have risen, leading to significant returns on investment for collectors.

Nonetheless, it's crucial to remember that investing in Pokemon cards comes with risks as factors like sales on eBay, card grade, and holofoil quality can impact the value.